Factor XI anticorps (C-Term)

N° du produit ABIN2788664

Détail du produit anti-Factor XI anticorps

Antigène: Factor XI (F11) (Coagulation Factor XI (F11))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Factor XI est non-conjugé

Application: Western Blotting (WB)

Séquence: RHLCGGSIIG NQWILTAAHC FYGVESPKIL RVYSGILNQS EIKEDTSFFG

Homologie: Cow: 100%, Dog: 79%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 82%, Rabbit: 93%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against F11. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human F11

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 625 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Factor XI

Antigène: Factor XI (F11) (Coagulation Factor XI (F11))

Autre désignation: F11 (F11 Produits)

Synonymes: anticorps FXI, anticorps 1600027G01Rik, anticorps AI503996, anticorps Cf11, anticorps LRRGT00086, anticorps coagulation factor XI, anticorps F11, anticorps CpipJ_CPIJ000593, anticorps CpipJ_CPIJ001060, anticorps CpipJ_CPIJ002752, anticorps CpipJ_CPIJ003631, anticorps CpipJ_CPIJ004041, anticorps CpipJ_CPIJ004093

Sujet: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.
Alias Symbols: FXI, MGC141891
Protein Interaction Partner: TFPI2, F11, SERPINA5, SERPINF2, KNG1, F2, HGF,
Protein Size: 625

Poids moléculaire: 70 kDa

ID gène: 2160

NCBI Accession: NM_000128, NP_000119

UniProt: P03951