TPR anticorps (C-Term)

N° du produit ABIN2788674

Détail du produit anti-TPR anticorps

Antigène: TPR (Nucleoprotein TPR (TPR))

Épitope: C-Term

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Lapin, Rat, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: SSEAGLEIDS QQEEEPVQAS DESDLPSTSQ DPPSSSSVDT SSSQPKPFRR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TPR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TPR

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 2363 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TPR

Antigène: TPR (Nucleoprotein TPR (TPR))

Autre désignation: TPR (TPR Produits)

Synonymes: anticorps AtTPR, anticorps TRANSLOCATED PROMOTER REGION, anticorps YUP8H12R.12, anticorps YUP8H12R_12, anticorps nuclear pore anchor, anticorps 2610029M07Rik, anticorps C77892, anticorps translocated promoter region, nuclear basket protein, anticorps nuclear pore anchor, anticorps TPR, anticorps NUA, anticorps Tpr

Sujet: This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.
Alias Symbols: -
Protein Interaction Partner: STAU1, UBC, LGR4, MDM2, MAD1L1, EED, NPM1, LMNA, HDAC9, ITGA4, FN1, CBX7, BUD31, TAF15, TOP1, SNRPD1, SNRPA1, SRSF5, SFPQ, S100A9, RPL37A, RPL18A, RPL6, RBM4, RAN, PRKDC, NHP2L1, SEPT2, IK, HRAS, HNRNPU, HNRNPA2B1, EEF1D, EEF1B2, DDX3X, DDX1, DDB1, CIRBP,
Protein Size: 2363

Poids moléculaire: 267 kDa

ID gène: 7175

NCBI Accession: NM_003292, NP_003283

UniProt: P12270