SOD1 anticorps (C-Term)
Aperçu rapide pour SOD1 anticorps (C-Term) (ABIN2788679)
Antigène
Voir toutes SOD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- DVSIEDSVIS LSGDHCIIGR TLVVHEKADD LGKGGNEEST KTGNAGSRLA
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Homologie
- Cow: 100%, Dog: 86%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against SOD1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human SOD1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
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Autre désignation
- SOD1
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Sujet
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SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in its gene have been implicated as causes of familial amyotrophic lateral sclerosis.
Alias Symbols: ALS, ALS1, IPOA, SOD, hSod1, homodimer
Protein Interaction Partner: SOD1, CRYAB, UBC, SMAD2, HDAC6, GSH1, OPTN, PRDX5, AHCYL1, TIAL1, PRDX2, SPTBN1, SOD2, PPP2CA, PPIA, PLS3, PRDX1, NME2, NME1, Hspa4l, Hspa4, Hspa2, Hspa1b, Hsph1, Dnaja1, Hspa8, Hspa5, Ccs, UBE3A, COMMD1, Stub1, SUMO4, DYNLT1, AMFR, MARCH5, RNF19A, PSMD4,
Protein Size: 154 -
Poids moléculaire
- 17 kDa
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ID gène
- 6647
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NCBI Accession
- NM_000454, NP_000445
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UniProt
- P00441
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Pathways
- Sensory Perception of Sound, Transition Metal Ion Homeostasis
Antigène
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