NQO1 anticorps (C-Term)

N° du produit ABIN2788701

Cet anticorps Lapin Polyclonal détecte spécifiquement NQO1 dans WB. Il présente une réactivité envers Humain, Rat, Chien, Lapin et Boeuf (Vache).

Aperçu rapide pour NQO1 anticorps (C-Term) (ABIN2788701)

Antigène: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Reactivité: Humain, Rat, Chien, Lapin, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NQO1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NQO1 anticorps

Épitope: C-Term

Séquence: WKKRLENIWD ETPLYFAPSS LFDLNFQAGF LMKKEVQDEE KNKKFGLSVG

Homologie: Cow: 86%, Dog: 79%, Human: 100%, Rabbit: 91%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against NQO1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human NQO1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 274 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NQO1

Antigène: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Autre désignation: NQO1

Sujet: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: DHQU, DIA4, DTD, NMOR1, NMORI, QR1
Protein Interaction Partner: UBC, FOS, NEDD8, SUMO1, NFE2L2, PARP1, BAG3, ITGA4, FN1, RPS10P5, POLDIP3, YTHDF1, RPS19, LAMB1, TP53, STUB1, ING1, DNAJB1, HSPA1A, NQO1, HSPA4,
Protein Size: 274

Poids moléculaire: 31 kDa

ID gène: 1728

NCBI Accession: NM_000903, NP_000894

UniProt: P15559