FMO2 anticorps (N-Term)
Aperçu rapide pour FMO2 anticorps (N-Term) (ABIN2788732)
Antigène
Voir toutes FMO2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- N-Term
-
Fonction
- FMO2 Antibody - N-terminal region
-
Séquence
- KYIQFQTTVL SVRKCPDFSS SGQWKVVTQS NGKEQSAVFD AVMVCSGHHI
-
Homologie
- Cow: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 85%, Rabbit: 93%, Rat: 100%
-
Attributs du produit
- This is a rabbit polyclonal antibody against FMO2. It was validated on Western Blot.
-
Purification
- Affinity Purified
-
Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human FMO2
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Commentaires
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61234-100UG
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.5 mg/mL
-
Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- prevent freeze-thaw cycles
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- FMO2 (Flavin Containing Monooxygenase 2 (Non-Functional) (FMO2))
-
Autre désignation
- FMO2
-
Sujet
-
Background Information: The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.
Gene Name: Flavin containing monooxygenase 2 (non-functional)
Alternative Symbols: FMO1B1
Protein Name: Dimethylaniline monooxygenase [N-oxide-forming] 2
-
Poids moléculaire
- 54kDa
-
ID gène
- 2327
-
NCBI Accession
- NP_001451
-
UniProt
- Q99518
Antigène
-