UGDH anticorps (C-Term)

N° du produit ABIN2788735

Cet anticorps Lapin Polyclonal détecte spécifiquement UGDH dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien et Cobaye.

Aperçu rapide pour UGDH anticorps (C-Term) (ABIN2788735)

Antigène: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UGDH est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-UGDH anticorps

Épitope: C-Term

Séquence: VLDGLHNELQ TIGFQIETIG KKVSSKRIPY APSGEIPKFS LQDPPNKKPK

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against UGDH. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 494 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur UGDH

Antigène: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Autre désignation: UGDH

Sujet: The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia.
Alias Symbols: GDH, UDP-GlcDH, UDPGDH, UGD
Protein Interaction Partner: UGDH, CIAO1, SUMO2, UBC, XPO5, MAT2B, RPUSD2, GORASP2, BOP1, RNASEH2A, ATG7, PDIA6, SNX1, PRKACA, ME1, MAT2A, GTF2A1, GARS, CTTN, BAG3, UGT1A1, RAD51, UBE2V1, TKT, ELAVL1, SIRT1, SIRT3, TERF2, AK5,
Protein Size: 494

Poids moléculaire: 54 kDa

ID gène: 7358

NCBI Accession: NM_003359, NP_003350

UniProt: O60701

Pathways: Glycosaminoglycan Metabolic Process