H2AFZ anticorps (N-Term)

N° du produit ABIN2788776

Détail du produit anti-H2AFZ anticorps

Antigène: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Mouton, Chien, Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp H2AFZ est non-conjugé

Application: Western Blotting (WB)

Séquence: AGGKAGKDSG KAKTKAVSRS QRAGLQFPVG RIHRHLKSRT TSHGRVGATA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against H2AFZ. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 128 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur H2AFZ

Antigène: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Autre désignation: H2AFZ (H2AFZ Produits)

Synonymes: anticorps H2A.Z-1, anticorps H2A.z, anticorps H2A/z, anticorps H2AZ, anticorps H2A.Z, anticorps H2a.z-1, anticorps H2AFV, anticorps H2Az, anticorps XH2AZ, anticorps h2a.zl1, anticorps h2a.zl2, anticorps H2A histone family member Z, anticorps H2A histone family, member Z, anticorps H2A histone family member Z L homeolog, anticorps histone H2A.Z, anticorps H2AFZ, anticorps H2afz, anticorps h2afz.L

Sujet: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
Alias Symbols: H2A.z, H2A/z, H2AZ, MGC117173
Protein Interaction Partner: UBC, ASB9, ASB16, WWOX, ZBTB1, OGFOD1, TRNT1, ACAA2, NOL3, EZR, PYGL, PSMD9, FH, UBD, PAN2, HIST1H3B, CENPA, MAGEC1, SUMO1, SUMO3, NEDD8, EPC1, MEAF6, ACTR6, EP400, DMAP1, MRGBP, ING3, MORF4L1, RUVBL2, SRCAP, KAT5, RUVBL1, TRRAP, YEATS4, VPS72, ACTL6A, HI
Protein Size: 128

Poids moléculaire: 14 kDa

ID gène: 3015

NCBI Accession: NM_002106, NP_002097

UniProt: P0C0S5

Pathways: Telomere Maintenance