F11R anticorps (C-Term)
Aperçu rapide pour F11R anticorps (C-Term) (ABIN2788778)
Antigène
Voir toutes F11R AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- F11R Antibody - C-terminal region
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Séquence
- AVLVTLILLG ILVFGIWFAY SRGHFDRTKK GTSSKKVIYS QPSARSEGEF
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Homologie
- Cow: 85%, Dog: 92%, Human: 100%, Pig: 92%, Rabbit: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against F11R. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61361-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- F11R (F11 Receptor (F11R))
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Autre désignation
- F11R
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Sujet
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Background Information: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Gene Name: F11 receptor
Alternative Symbols: JAM, KAT, JAM1, JAMA, JCAM, CD321, PAM-1
Protein Name: Junctional adhesion molecule A
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Poids moléculaire
- 33kDa
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ID gène
- 50848
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NCBI Accession
- NP_058642
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UniProt
- Q9Y624
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Pathways
- Cell-Cell Junction Organization
Antigène
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