CysLTR1 anticorps (C-Term)
Aperçu rapide pour CysLTR1 anticorps (C-Term) (ABIN2788780)
Antigène
Voir toutes CysLTR1 (CYSLTR1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- IIPFVIIIVC YTMIILTLLK KSMKKNLSSH KKAIGMIMVV TAAFLVSFMP
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Homologie
- Cow: 93%, Dog: 86%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Rabbit: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against CYSLTR1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 337 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))
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Autre désignation
- CYSLTR1
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Sujet
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The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
Alias Symbols: CYSLT1, CYSLT1R, CYSLTR, HG55, HMTMF81, MGC46139
Protein Interaction Partner: CYSLTR2,
Protein Size: 337 -
Poids moléculaire
- 37 kDa
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ID gène
- 10800
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NCBI Accession
- NM_006639, NP_006630
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UniProt
- Q9Y271
Antigène
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