ABI2 anticorps (N-Term)

N° du produit ABIN2788799

Cet anticorps Lapin Polyclonal détecte spécifiquement ABI2 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Cobaye, Lapin, Boeuf (Vache), Chien, Cheval, Saccharomyces cerevisiae et Poisson zèbre (Danio rerio).

Aperçu rapide pour ABI2 anticorps (N-Term) (ABIN2788799)

Antigène: ABI2 (Abl-Interactor 2 (ABI2))

Reactivité: Humain, Souris, Rat, Cobaye, Lapin, Boeuf (Vache), Chien, Cheval, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABI2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ABI2 anticorps

Épitope: N-Term

Séquence: MLLEEEIPGG RRALFDSYTN LERVADYCEN NYIQSADKQR ALEETKAYTT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 83%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against ABI2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ABI2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 475 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ABI2

Antigène: ABI2 (Abl-Interactor 2 (ABI2))

Autre désignation: ABI2

Sujet: ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. ABI2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA.
Alias Symbols: ABI-2, ABI2B, AIP-1, AblBP3, SSH3BP2, argBPIA, argBPIB
Protein Interaction Partner: CCDC36, MRFAP1L1, EGLN3, IFT20, PRAM1, CCDC102B, ARMC7, GCC1, MRPL44, VARS2, KIAA1217, CCHCR1, PRR16, BLOC1S6, TFIP11, NUP62, TRIM32, EFS, STAM2, ABI2, PPIF, ARHGAP32, HOMER3, HGS, EIF3H, NCK2, WIPF1, VASP, TRIP6, SDCBP, PRKAA2, PRKAA1, PIN1, LMO2, KRT33B
Protein Size: 475

Poids moléculaire: 52 kDa

ID gène: 10152

NCBI Accession: NM_005759, NP_005750

UniProt: Q9NYB9