ABI2 anticorps (N-Term)

N° du produit ABIN2788799

Détail du produit anti-ABI2 anticorps

Antigène: ABI2 (Abl-Interactor 2 (ABI2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Cobaye, Lapin, Boeuf (Vache), Chien, Cheval, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABI2 est non-conjugé

Application: Western Blotting (WB)

Séquence: MLLEEEIPGG RRALFDSYTN LERVADYCEN NYIQSADKQR ALEETKAYTT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 83%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against ABI2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ABI2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 475 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ABI2

Antigène: ABI2 (Abl-Interactor 2 (ABI2))

Autre désignation: ABI2 (ABI2 Produits)

Synonymes: anticorps ABI-2, anticorps ABI2B, anticorps AIP-1, anticorps AblBP3, anticorps SSH3BP2, anticorps argBPIA, anticorps argBPIB, anticorps 8430425M24Rik, anticorps AI839867, anticorps C130078H13, anticorps abl interactor 2, anticorps abl-interactor 2, anticorps ABI2, anticorps abi2, anticorps Abi2

Sujet: ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. ABI2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA.
Alias Symbols: ABI-2, ABI2B, AIP-1, AblBP3, SSH3BP2, argBPIA, argBPIB
Protein Interaction Partner: CCDC36, MRFAP1L1, EGLN3, IFT20, PRAM1, CCDC102B, ARMC7, GCC1, MRPL44, VARS2, KIAA1217, CCHCR1, PRR16, BLOC1S6, TFIP11, NUP62, TRIM32, EFS, STAM2, ABI2, PPIF, ARHGAP32, HOMER3, HGS, EIF3H, NCK2, WIPF1, VASP, TRIP6, SDCBP, PRKAA2, PRKAA1, PIN1, LMO2, KRT33B
Protein Size: 475

Poids moléculaire: 52 kDa

ID gène: 10152

NCBI Accession: NM_005759, NP_005750

UniProt: Q9NYB9