LGI1 anticorps (N-Term)
Aperçu rapide pour LGI1 anticorps (N-Term) (ABIN2788819)
Antigène
Voir toutes LGI1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- LLSALLLTEG KKPAKPKCPA VCTCTKDNAL CENARSIPRT VPPDVISLSF
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against LGI1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 557 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))
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Autre désignation
- LGI1
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Sujet
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This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy.
Alias Symbols: EPITEMPIN, EPT, ETL1, IB1099, ADLTE, ADPAEF
Protein Interaction Partner: ADAM22, DLG4,
Protein Size: 557 -
Poids moléculaire
- 61 kDa
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ID gène
- 9211
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NCBI Accession
- NM_005097, NP_005088
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UniProt
- O95970
Antigène
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