Cet anticorps Lapin Polyclonal détecte spécifiquement PDLIM7 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye et Poisson zèbre (Danio rerio).
PDLIM7
Reactivité: Humain
WB, IP
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeat freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Antigène
PDLIM7
(PDZ and LIM Domain 7 (Enigma) (PDLIM7))
Autre désignation
PDLIM7
Sujet
The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. Protein Interaction Partner: WWP2, IQGAP1, TSG101, PHF1, DGCR6, BAG3, RET, CBLC, COPS5, PARP1, YAP1, HNRNPD, PRKD2, ZMYND11, TRADD, UBC, SH3BP2, MYC, Hoxa1, NDUFA7, PCBP1, UBQLN4, TRAF3, TRAF2, TAB2, TRAF6, NR2C2, SMURF1, TP53, MDM2, Cdk1, PSMF1, SH2B2, C20orf195, AP5B1, ENKD1, TPM2, Protein Size: 287