PDLIM7 anticorps (N-Term)
Aperçu rapide pour PDLIM7 anticorps (N-Term) (ABIN2788823)
Antigène
Voir toutes PDLIM7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- RLMENTEDWR PRPGTGQSRS FRILAHLTGT EFMQDPDEEH LKKSSQVPRT
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Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against PDLIM7. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of HUMAN PDLIM7
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PDLIM7 (PDZ and LIM Domain 7 (Enigma) (PDLIM7))
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Autre désignation
- PDLIM7
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Sujet
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The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.
Protein Interaction Partner: WWP2, IQGAP1, TSG101, PHF1, DGCR6, BAG3, RET, CBLC, COPS5, PARP1, YAP1, HNRNPD, PRKD2, ZMYND11, TRADD, UBC, SH3BP2, MYC, Hoxa1, NDUFA7, PCBP1, UBQLN4, TRAF3, TRAF2, TAB2, TRAF6, NR2C2, SMURF1, TP53, MDM2, Cdk1, PSMF1, SH2B2, C20orf195, AP5B1, ENKD1, TPM2,
Protein Size: 287 -
Poids moléculaire
- 31 kDa
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ID gène
- 9260
Antigène
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