Melatonin Receptor 1A anticorps (C-Term)
Aperçu rapide pour Melatonin Receptor 1A anticorps (C-Term) (ABIN2788825)
Antigène
Voir toutes Melatonin Receptor 1A (MTNR1A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- GLLNQNFRKE YRRIIVSLCT ARVFFVDSSN DVADRVKWKP SPLMTNNNVV
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Homologie
- Cow: 79%, Dog: 91%, Goat: 79%, Guinea Pig: 82%, Horse: 83%, Human: 100%, Rabbit: 83%, Sheep: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against MTNR1A. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 350 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Melatonin Receptor 1A (MTNR1A)
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Autre désignation
- MTNR1A
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Sujet
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This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
Alias Symbols: MEL-1A-R, MT1
Protein Interaction Partner: VAPB, IRS4, RAP1A, RAC1, HSPA5, GNB1, GNAI3, GNAI2, GNAI1, GNB4, LRRC59, TMEM33, HNRNPA0, RAB10, PGRMC1, PDIA6, FLNA, EEF1G, CNP, CANX, CALR, GPR50, GNA13, DPM1, MTNR1B, MTNR1A, GNA11,
Protein Size: 350 -
Poids moléculaire
- 39 kDa
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ID gène
- 4543
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NCBI Accession
- NM_005958, NP_005949
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UniProt
- P48039
Antigène
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