EIF5B anticorps (Middle Region)
Aperçu rapide pour EIF5B anticorps (Middle Region) (ABIN2788862)
Antigène
Voir toutes EIF5B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- SEGSEGDEED EKVSDEKDSG KTLDKKPSKE MSSDSEYDSD DDRTKEERAY
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Homologie
- Cow: 86%, Dog: 86%, Horse: 86%, Human: 100%, Pig: 93%, Rabbit: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against EIF5B. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 1220 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- EIF5B (Eukaryotic Translation Initiation Factor 5B (EIF5B))
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Autre désignation
- EIF5B
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Sujet
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Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.
Alias Symbols: DKFZp434I036, FLJ10524, IF2, KIAA0741
Protein Interaction Partner: TP53, TFCP2, UBC, LGR4, YBX3, ETS1, MMS19, FN1, CSNK2A1, PAXIP1, ECT2, BRCA1, EIF3C, CAND1, YWHAZ, SIRT7, HDGF, Mapk13, POU5F1, ZBTB3, PRKAA1, EIF1AX, CBL, gag,
Protein Size: 1220 -
Poids moléculaire
- 139 kDa
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ID gène
- 9669
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NCBI Accession
- NM_015904, NP_056988
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UniProt
- O60841
Antigène
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