EIF3A anticorps (C-Term)

N° du produit ABIN2788872

Détail du produit anti-EIF3A anticorps

Antigène: EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Poisson zèbre (Danio rerio), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF3A est non-conjugé

Application: Western Blotting (WB)

Séquence: PPALSRDRER DRDREREGEK EKASWRAEKD RESLRRTKNE TDEDGWTTVR

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against EIF3A. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1382 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur EIF3A

Antigène: EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))

Autre désignation: EIF3A (EIF3A Produits)

Synonymes: anticorps EIF3, anticorps EIF3S10, anticorps P167, anticorps TIF32, anticorps eIF3-p170, anticorps eIF3-theta, anticorps p180, anticorps p185, anticorps EIF6, anticorps A830012B05Rik, anticorps Csma, anticorps Eif3, anticorps Eif3s10, anticorps mKIAA0139, anticorps ZH12, anticorps eif3s10, anticorps eIF3 p110, anticorps eIF3a, anticorps eukaryotic translation initiation factor 3 subunit A, anticorps eukaryotic translation initiation factor 3, subunit A, anticorps eukaryotic translation initiation factor 3 subunit A S homeolog, anticorps translation initiation factor eIF3a, anticorps EIF3A, anticorps Eif3a, anticorps eif3a.S, anticorps tif32

Sujet: EIF3A is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Alias Symbols: EIF3, EIF3S10, KIAA0139, P167, TIF32, eIF3-p170, eIF3-theta, p180, p185
Protein Interaction Partner: UBC, REL, TFIP11, WWP2, SUMO2, STAU1, LGR4, WWOX, EED, SHFM1, RNF2, EIF3CL, YTHDF2, LARP1, NUDT21, EIF3C, DYNC1I2, RPS26, RPS25, RPS23, RPS20, RPS18, RPS12, RPS10, RPS9, RPS3A, RPS3, FBXO6, TARDBP, EIF3D, UBD, ICAM1, CD81, RIOK2, IGSF8, BBS4, BBS1, gag-po
Protein Size: 1382

Poids moléculaire: 152 kDa

ID gène: 8661

NCBI Accession: NM_003750, NP_003741

UniProt: Q14152

Pathways: Ribonucleoprotein Complex Subunit Organization