RPL7A anticorps (C-Term)
Aperçu rapide pour RPL7A anticorps (C-Term) (ABIN2788883)
Antigène
Voir toutes RPL7A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- KLVEAIRTNY NDRYDEIRRH WGGNVLGPKS VARIAKLEKA KAKELATKLG
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against RPL7A. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 266 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RPL7A (Ribosomal Protein L7a (RPL7A))
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Autre désignation
- RPL7A
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Sujet
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Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Alias Symbols: SURF3, TRUP, L7A
Protein Interaction Partner: HUWE1, UBC, TP53, SUMO2, CEP250, STAU1, MDM2, EED, RNF2, EEF1E1, AIMP1, DARS, RPL36, RPLP0, RPL26, RPL23A, RPL21, RPL15, RPL13, QARS, EIF2S1, TRAP1, PARK2, FBXO6, TARDBP, IGSF8, ICAM1, PAN2, SOCS3, UBL4A, VCAM1, ITGA4, FN1, CTBP2, MAGOH, EIF4A3, UPF1, ESR
Protein Size: 266 -
Poids moléculaire
- 29 kDa
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ID gène
- 6130
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NCBI Accession
- NM_000972, NP_000963
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UniProt
- P62424
Antigène
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