Cyclin-Dependent Kinase 11A (CDK11A) (C-Term) anticorps

N° du produit ABIN2788912

Cet anticorps Lapin Polyclonal détecte spécifiquement Cyclin-Dependent Kinase 11A dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Chien, Rat, Boeuf (Vache), Cheval, Lapin, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour Cyclin-Dependent Kinase 11A (CDK11A) (C-Term) anticorps (ABIN2788912)

Antigène: Cyclin-Dependent Kinase 11A (CDK11A)

Reactivité: Humain, Souris, Chien, Rat, Boeuf (Vache), Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Détail du produit

Épitope: C-Term

Fonction: CDK11A Antibody - C-terminal region

Séquence: EYFRETPLPI DPSMFPTWPA KSEQQRVKRG TSPRPPEGGL GYSQLGDDDL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CDK11A. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61814-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détail du antigène

Antigène: Cyclin-Dependent Kinase 11A (CDK11A)

Autre désignation: CDK11A

Sujet:

Background Information: This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L1, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L1, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions, which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L1 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Many transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of only two have been determined so far.

Gene Name: Cyclin-dependent kinase 11A

Alternative Symbols: CDC2L2, CDC2L3, p58GTA, PITSLRE, CDK11-p46, CDK11-p58, CDK11-p110

Protein Name: Cyclin-dependent kinase 11A

Poids moléculaire: 84kDa

ID gène: 728642

NCBI Accession: NP_277071

UniProt: Q9UQ88

Pathways: M Phase