VNN2 anticorps (C-Term)

N° du produit ABIN2788913

Détail du produit anti-VNN2 anticorps

Antigène: VNN2 (Vanin 2 (VNN2))

Épitope: C-Term

Reactivité: Humain, Boeuf (Vache), Cheval, Mouton, Poisson zèbre (Danio rerio), Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VNN2 est non-conjugé

Application: Western Blotting (WB)

Séquence: FRGFISRDGF NFTELFENAG NLTVCQKELC CHLSYRMLQK EENEVYVLGA

Homologie: Cow: 79%, Dog: 89%, Horse: 86%, Human: 100%, Pig: 93%, Sheep: 86%, Zebrafish: 75%

Attributs du produit: This is a rabbit polyclonal antibody against VNN2. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 520 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur VNN2

Antigène: VNN2 (Vanin 2 (VNN2))

Autre désignation: VNN2 (VNN2 Produits)

Sujet: This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: FOAP-4, GPI-80
Protein Interaction Partner: ITGB2,
Protein Size: 520

Poids moléculaire: 57 kDa

ID gène: 8875

NCBI Accession: NM_004665, NP_004656

UniProt: O95498