ARFGAP3 anticorps (C-Term)
Aperçu rapide pour ARFGAP3 anticorps (C-Term) (ABIN2788930)
Antigène
Voir toutes ARFGAP3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- SYWKKETSKD TETVLKTTGY SDRPTARRKP DYEPVENTDE AQKKFGNVKA
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Homologie
- Cow: 86%, Dog: 100%, Horse: 93%, Human: 100%, Pig: 79%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against ARFGAP3. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 516 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))
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Autre désignation
- ARFGAP3
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Sujet
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The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.
Alias Symbols: ARFGAP1, FLJ45618
Protein Interaction Partner: UBC, CXCL8, CD14, APP, SMAD2,
Protein Size: 516 -
Poids moléculaire
- 57 kDa
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ID gène
- 26286
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NCBI Accession
- NM_014570, NP_055385
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UniProt
- Q9NP61
Antigène
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