CDK14 anticorps (C-Term)

N° du produit ABIN2788962

Détail du produit anti-CDK14 anticorps

Antigène: CDK14 (Cyclin-Dependent Kinase 14 (CDK14))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Porc, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK14 est non-conjugé

Application: Western Blotting (WB)

Séquence: SDLPPRLWEL TDMSSIFTVP NVRLQPEAGE SMRAFGKNNS YGKSLSNSKH

Homologie: Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Cdk14. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 469 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CDK14

Antigène: CDK14 (Cyclin-Dependent Kinase 14 (CDK14))

Autre désignation: Cdk14 (CDK14 Produits)

Synonymes: anticorps PFTK1, anticorps PFTAIRE1, anticorps Pftk1, anticorps mKIAA0834, anticorps pftaire1, anticorps pftk1, anticorps cyclin dependent kinase 14, anticorps cyclin-dependent kinase 14, anticorps cyclin-dependent kinase 14 L homeolog, anticorps CDK14, anticorps Cdk14, anticorps cdk14.L

Sujet: Cdk14 is a Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Cdk14 acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Cdk14 acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. Cdk14 may also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.
Alias Symbols: Pftk1, mKIAA0834
Protein Interaction Partner: SMURF1, TGFBR1, BMPR1B, ACVR1,
Protein Size: 469

Poids moléculaire: 53 kDa

ID gène: 18647

NCBI Accession: NM_011074, NP_035204

UniProt: O35495