CDK14 anticorps (C-Term)

N° du produit ABIN2788962

L’anticorps anti-CDK14 Polyclonal Lapin est utilisé pour la détection de CDK14 dans des échantillons de Humain, Souris, Rat, Chien, Porc, Cobaye, Cheval et Lapin. Il a été validé pour WB.

Aperçu rapide pour CDK14 anticorps (C-Term) (ABIN2788962)

Antigène: CDK14 (Cyclin-Dependent Kinase 14 (CDK14))

Reactivité: Humain, Souris, Rat, Chien, Porc, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK14 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CDK14 anticorps

Épitope: C-Term

Fonction: Cdk14 Antibody - C-terminal region

Séquence: SDLPPRLWEL TDMSSIFTVP NVRLQPEAGE SMRAFGKNNS YGKSLSNSKH

Homologie: Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Cdk14. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61958-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CDK14

Antigène: CDK14 (Cyclin-Dependent Kinase 14 (CDK14))

Autre désignation: Cdk14

Sujet:

Background Information: Cdk14 is a Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Cdk14 acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Cdk14 acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. Cdk14 may also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.

Gene Name: Cyclin-dependent kinase 14

Alternative Symbols: Pftk, Pftk1, mKIAA0834

Protein Name: Cyclin-dependent kinase 14

Poids moléculaire: 53kDa

ID gène: 18647

NCBI Accession: NP_035204

UniProt: O35495