NPLOC4 anticorps (N-Term)
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- Antigène Voir toutes NPLOC4 Anticorps
- NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))
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Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NPLOC4 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GLKAFGAPNV VEDEIDQYLS KQDGKIYRSR DPQLCRHGPL GKCVHCVPLE
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against Nploc4. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Nploc4
- Top Product
- Discover our top product NPLOC4 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 608 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))
- Autre désignation
- Nploc4 (NPLOC4 Produits)
- Synonymes
- anticorps NPL4, anticorps AK129375, anticorps Npl4, anticorps mKIAA1499, anticorps NPL4 homolog, ubiquitin recognition factor, anticorps NPLOC4, anticorps Nploc4
- Sujet
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The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope.
Alias Symbols: AK129375, Npl4, mKIAA1499
Protein Interaction Partner: Map3k1, Vcp, Ubc, Itpr1,
Protein Size: 608 - Poids moléculaire
- 66 kDa
- ID gène
- 217365
- NCBI Accession
- NM_001195023, NP_001181952
- UniProt
- P60670
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