CTPS2 anticorps (N-Term)

N° du produit ABIN2789147

Détail du produit anti-CTPS2 anticorps

Antigène: CTPS2 (CTP Synthase II (CTPS2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Porc, Lapin, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTPS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: AKRENFCNIH VSLVPQLSAT GEQKTKPTQN SVRALRGLGL SPDLIVCRSS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CTPS2. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 586 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CTPS2

Antigène: CTPS2 (CTP Synthase II (CTPS2))

Autre désignation: CTPS2 (CTPS2 Produits)

Synonymes: anticorps A830031M15Rik, anticorps AI326475, anticorps Ctpsh, anticorps CTP synthase 2 L homeolog, anticorps CTP synthase 2, anticorps cytidine 5'-triphosphate synthase 2, anticorps ctps2.L, anticorps CTPS2, anticorps ctps2, anticorps Ctps2

Sujet: The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.
Alias Symbols: DKFZp686C17207, FLJ43358, MGC32997
Protein Interaction Partner: CTPS2, SPG21, RNF2, LRSAM1, EHD4, EHD1, PLIN3, MTMR2, WARS, PRKDC, NUCB1, METTL1, KTN1, HSF1, GTF2I, DHPS, RPL37A, RPL23A, FGFR1, CTBP2, UBC, SUMO2, OTUD5,
Protein Size: 586

Poids moléculaire: 64 kDa

ID gène: 56474

NCBI Accession: NM_175859, NP_787055

UniProt: Q9NRF8

Pathways: Ribonucleoside Biosynthetic Process