DCTN3 anticorps (C-Term)

N° du produit ABIN2789148

L’anticorps Lapin Polyclonal anti-DCTN3 a été validé pour WB. Il convient pour détecter DCTN3 dans des échantillons de Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour DCTN3 anticorps (C-Term) (ABIN2789148)

Antigène: DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCTN3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DCTN3 anticorps

Épitope: C-Term

Séquence: ARLQRLAQIH IQQQDQCVEI TEESKALLEE YNKTTMLLSK QFVQWDELLC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against DCTN3. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 186 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DCTN3

Antigène: DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))

Autre désignation: DCTN3

Sujet: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants.
Alias Symbols: DCTN-22, DCTN22, MGC111190
Protein Interaction Partner: LMNB1, FLNB, FHL2, LEO1, TNKS1BP1, NUP85, CCAR2, ACTR10, DCTN2, ACTR1A, UBC, ACTR1B, DYNLT3, ATXN1, GSK3B, Dctn3, Dctn1, Capza1, PBX2,
Protein Size: 186

Poids moléculaire: 20 kDa

ID gène: 11258

NCBI Accession: NM_001248, NP_001239

UniProt: O75355

Pathways: M Phase