EEF1E1 anticorps (N-Term)

N° du produit ABIN2789165

Cet anticorps Lapin Polyclonal détecte spécifiquement EEF1E1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Cobaye et Chien.

Aperçu rapide pour EEF1E1 anticorps (N-Term) (ABIN2789165)

Antigène: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Cobaye, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EEF1E1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-EEF1E1 anticorps

Épitope: N-Term

Séquence: IPVLQTNNGP SLTGLTTIAA HLVKQANKEY LLGSTAEEKA IVQQWLEYRV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against EEF1E1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 174 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur EEF1E1

Antigène: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Autre désignation: EEF1E1

Sujet: This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.
Alias Symbols: AIMP3, P18
Protein Interaction Partner: NAT9, CALCOCO2, HUWE1, RPLP0, RPL27A, RPL26, RPL24, RPL23A, RPL21, RPL18, RPL15, RPL13, RPL7A, QARS, MARS, CCAR2, RPL36, AIMP1, IQGAP1, AIMP2, IARS, DNAJA1, HNRNPA2B1, EIF4G1, EIF2S3, EIF2S1, DARS, gag, UBC, ITGA4, RARS, KARS, EPRS, ATR, ATM,
Protein Size: 174

Poids moléculaire: 19 kDa

ID gène: 9521

NCBI Accession: NM_004280, NP_004271

UniProt: O43324

Pathways: Positive Regulation of Response to DNA Damage Stimulus