SIK2 anticorps (N-Term)

N° du produit ABIN2789222

Détail du produit anti-SIK2 anticorps

Antigène: SIK2 (Salt-Inducible Kinase 2 (SIK2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIK2 est non-conjugé

Application: Western Blotting (WB)

Séquence: VLYPQEQENE PSIGEFNEQV LRLMHSLGID QQKTIESLQN KSYNHFAAIY

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SIK2. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 926 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SIK2

Antigène: SIK2 (Salt-Inducible Kinase 2 (SIK2))

Autre désignation: SIK2 (SIK2 Produits)

Synonymes: anticorps PIG33, anticorps SC1, anticorps LOH11CR1I, anticorps QIK, anticorps SNF1LK2, anticorps G630080D20Rik, anticorps Snf1lk2, anticorps RGD1559698, anticorps si:dkey-27p23.1, anticorps snf1lk2a, anticorps SPARC like 1, anticorps salt inducible kinase 2, anticorps salt-inducible kinase 2, anticorps salt-inducible kinase 2a, anticorps SPARCL1, anticorps SIK2, anticorps SLK2, anticorps Sik2, anticorps sik2a

Sujet: SIK2 phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. It inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.
Alias Symbols: DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2
Protein Interaction Partner: GABARAPL2, YWHAZ, YWHAE, VCP, HSPA4, HDAC5, CEP250, UBC, APP, BMH1, CRTC2, YWHAQ, PRKAA1, IRS1,
Protein Size: 926

Poids moléculaire: 102 kDa

ID gène: 23235

NCBI Accession: NM_015191, NP_056006

UniProt: Q9H0K1