FPGT anticorps (C-Term)

N° du produit ABIN2789256

Cet anticorps anti-FPGT est un anticorps Lapin Polyclonal détectant FPGT dans WB. Adapté pour Humain, Souris, Cobaye, Boeuf (Vache), Chien, Porc et Rat.

Aperçu rapide pour FPGT anticorps (C-Term) (ABIN2789256)

Antigène: FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))

Reactivité: Humain, Souris, Cobaye, Boeuf (Vache), Chien, Porc, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FPGT est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FPGT anticorps

Épitope: C-Term

Séquence: TSLNVVVLNN SKFYHIGTTE EYLFYFTSDN SLKSELGLQS ITFSIFPDIP

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 79%, Pig: 100%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against FPGT. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human FPGT

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 594 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FPGT

Antigène: FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))

Autre désignation: FPGT

Sujet: L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose, the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene.
Alias Symbols: GFPP
Protein Interaction Partner: NLN,
Protein Size: 594

Poids moléculaire: 66 kDa

ID gène: 8790

NCBI Accession: NM_003838, NP_003829

UniProt: O14772