FPGT anticorps (C-Term)

N° du produit ABIN2789256

Cet anticorps anti-FPGT Polyclonal Lapin (ABIN2789256) détecte spécifiquement FPGT dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Cobaye, Boeuf (Vache), Chien, Porc et Rat.

Aperçu rapide pour FPGT anticorps (C-Term) (ABIN2789256)

Antigène: FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))

Reactivité: Humain, Souris, Cobaye, Boeuf (Vache), Chien, Porc, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FPGT est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FPGT anticorps

Épitope: C-Term

Fonction: FPGT Antibody - C-terminal region

Séquence: TSLNVVVLNN SKFYHIGTTE EYLFYFTSDN SLKSELGLQS ITFSIFPDIP

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 79%, Pig: 100%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against FPGT. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human FPGT

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62824-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur FPGT

Antigène: FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))

Autre désignation: FPGT

Sujet:

Background Information: L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose, the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene.

Gene Name: Fucose-1-phosphate guanylyltransferase

Alternative Symbols: GFPP

Protein Name: Fucose-1-phosphate guanylyltransferase

Poids moléculaire: 66kDa

ID gène: 8790

NCBI Accession: NP_003829

UniProt: O14772