Acrosin anticorps (C-Term)
Aperçu rapide pour Acrosin anticorps (C-Term) (ABIN2789340)
Antigène
Voir toutes Acrosin (ACR) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- GKIDTCQGDS GGPLMCKDSK ESAYVVVGIT SWGVGCARAK RPGIYTATWP
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Homologie
- Cow: 79%, Horse: 79%, Human: 100%, Sheep: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against ACR. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 421 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Acrosin (ACR)
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Autre désignation
- ACR
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Sujet
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Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
Alias Symbols: -
Protein Interaction Partner: TP53BP1, SERPINA5, ZP3, ZP2, E2F4,
Protein Size: 421 -
Poids moléculaire
- 46 kDa
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ID gène
- 49
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NCBI Accession
- NM_001097, NP_001088
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UniProt
- P10323
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Pathways
- cAMP Metabolic Process
Antigène
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