CD1a anticorps (C-Term)

N° du produit ABIN2789348

Cet anticorps Lapin Polyclonal détecte spécifiquement CD1a dans WB. Il présente une réactivité envers Humain, Souris, Chien, Rat, Porc, Boeuf (Vache), Cobaye, Cheval et Mouton.

Aperçu rapide pour CD1a anticorps (C-Term) (ABIN2789348)

Antigène: CD1a

Reactivité: Humain, Souris, Chien, Rat, Porc, Boeuf (Vache), Cobaye, Cheval, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD1a est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD1a anticorps

Épitope: C-Term

Séquence: KPEAWLSHGP SPGPGHLQLV CHVSGFYPKP VWVMWMRGEQ EQQGTQRGDI

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rat: 79%, Sheep: 79%

Attributs du produit: This is a rabbit polyclonal antibody against CD1A. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 327 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD1a

Antigène: CD1a

Autre désignation: CD1A

Sujet: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
Alias Symbols: CD1, FCB6, HTA1, R4, T6
Protein Interaction Partner: UBTD1, KCTD5, DGAT1, VWA5A, B2M,
Protein Size: 327

Poids moléculaire: 37 kDa

ID gène: 909

NCBI Accession: NM_001763, NP_001754

UniProt: P06126

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process