ALOX5 anticorps (C-Term)

N° du produit ABIN2789351

Détail du produit anti-ALOX5 anticorps

Antigène: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Lapin, Chien, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALOX5 est non-conjugé

Application: Western Blotting (WB)

Séquence: FGQLFLGMYP EEHFIEKPVK EAMARFRKNL EAIVSVIAER NKKKQLPYYY

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ALOX5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ALOX5

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ALOX5

Antigène: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Autre désignation: ALOX5 (ALOX5 Produits)

Synonymes: anticorps 5-LO, anticorps 5-LOX, anticorps 5LPG, anticorps LOG5, anticorps 5LO, anticorps 5LX, anticorps AI850497, anticorps F730011J02, anticorps LOX5A, anticorps si:dkey-194n13.2, anticorps lox5, anticorps arachidonate 5-lipoxygenase, anticorps arachidonate 5-lipoxygenase a, anticorps Arachidonate 5-lipoxygenase, anticorps ALOX5, anticorps Alox5, anticorps alox5a, anticorps AFUA_4G02770, anticorps AOR_1_1362014, anticorps lox5

Sujet: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: CEP57L1, NUTM1, SYCE1, CEP63, HHIPL2, COTL1, MAD1L1, REL, MEOX1, PIK3R1, DICER1, MAPKAPK2, LTC4S, ALOX5AP, APP, TGFBRAP1, GRB2, ACTB,
Protein Size: 617

Poids moléculaire: 67 kDa

ID gène: 240

NCBI Accession: NP_001243083

UniProt: B7ZLS0