ALOX5 anticorps (C-Term)

N° du produit ABIN2789351

L’anticorps anti-ALOX5 Polyclonal Lapin est utilisé pour la détection de ALOX5 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cheval et Cobaye. Il a été validé pour WB.

Aperçu rapide pour ALOX5 anticorps (C-Term) (ABIN2789351)

Antigène: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALOX5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ALOX5 anticorps

Épitope: C-Term

Fonction: ALOX5 Antibody - C-terminal region

Séquence: FGQLFLGMYP EEHFIEKPVK EAMARFRKNL EAIVSVIAER NKKKQLPYYY

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ALOX5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ALOX5

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63055-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ALOX5

Antigène: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Autre désignation: ALOX5

Sujet:

Background Information: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: arachidonate 5-lipoxygenase

Alternative Symbols: 5-LO, 5LPG, LOG5, 5-LOX

Protein Name: ALOX5 protein EMBL AAI43986.1

Poids moléculaire: 67kDa

ID gène: 240

NCBI Accession: NP_001243083

UniProt: B7ZLS0