PLAUR anticorps (N-Term)

N° du produit ABIN2789360

Cet anticorps Lapin Polyclonal détecte spécifiquement PLAUR dans WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour PLAUR anticorps (N-Term) (ABIN2789360)

Antigène: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAUR est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PLAUR anticorps

Épitope: N-Term

Fonction: PLAUR Antibody - N-terminal region

Séquence: ELELVEKSCT HSEKTNRTLS YRTGLKITSL TEVVCGLDLC NQGNSGRAVT

Homologie: Human: 100%, Mouse: 82%

Attributs du produit: This is a rabbit polyclonal antibody against PLAUR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of PLAUR

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63076-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PLAUR

Antigène: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Autre désignation: PLAUR

Sujet:

Background Information: This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

Alternative Symbols: CD87, UPAR, URKR, U-PAR

Protein Name: Urokinase plasminogen activator surface receptor

Poids moléculaire: 37kDa

ID gène: 5329

NCBI Accession: NP_002650

UniProt: Q9GK80

Pathways: Inositol Metabolic Process