L1CAM anticorps (C-Term)

N° du produit ABIN2789372

Cet anticorps Lapin Polyclonal détecte spécifiquement L1CAM dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Lapin, Cobaye, Cheval et Boeuf (Vache).

Aperçu rapide pour L1CAM anticorps (C-Term) (ABIN2789372)

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Lapin, Cobaye, Cheval, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp L1CAM est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-L1CAM anticorps

Épitope: C-Term

Séquence: GDIKPLGSDD SLADYGGSVD VQFNEDGSFI GQYSGKKEKE AAGGNDSSGA

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against L1CAM. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1257 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur L1CAM

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Autre désignation: L1CAM

Sujet: The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
Alias Symbols: CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAML1, S10, SPG1, NCAM-L1, N-CAM-L1
Protein Interaction Partner: RANBP9, FBXO6, NRP1, Caskin1, RABGEF1, UBC, EZR, CANX, CNTN1, NUMB, PEA15, RPS6KA2, RPS6KA1, NCAN, MSN, ITGAV, CNTN2, ANK1, RDX, PRNP, ITGA5, NCAM1, CSNK2A1, ANK2, AP2A1, AP2M1,
Protein Size: 1257

Poids moléculaire: 138 kDa

ID gène: 3897

NCBI Accession: NM_000425, NP_000416

UniProt: P32004

Pathways: Synaptic Membrane