L1CAM anticorps (C-Term)
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- Antigène Voir toutes L1CAM Anticorps
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
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Épitope
- C-Term
- Reactivité
- Humain, Souris, Rat, Chien, Lapin, Poisson zèbre (Danio rerio), Cobaye, Cheval, Boeuf (Vache)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp L1CAM est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GDIKPLGSDD SLADYGGSVD VQFNEDGSFI GQYSGKKEKE AAGGNDSSGA
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against L1CAM. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product L1CAM Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1257 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
- Autre désignation
- L1CAM (L1CAM Produits)
- Synonymes
- anticorps l1cam-a, anticorps CAML1, anticorps CD171, anticorps HSAS, anticorps HSAS1, anticorps MASA, anticorps MIC5, anticorps N-CAM-L1, anticorps N-CAML1, anticorps NCAM-L1, anticorps S10, anticorps SPG1, anticorps L1, anticorps Hsas, anticorps Hyd, anticorps NCAML1, anticorps L1 cell adhesion molecule S homeolog, anticorps L1 cell adhesion molecule, anticorps l1cam.S, anticorps L1CAM, anticorps L1cam
- Sujet
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The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
Alias Symbols: CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAML1, S10, SPG1, NCAM-L1, N-CAM-L1
Protein Interaction Partner: RANBP9, FBXO6, NRP1, Caskin1, RABGEF1, UBC, EZR, CANX, CNTN1, NUMB, PEA15, RPS6KA2, RPS6KA1, NCAN, MSN, ITGAV, CNTN2, ANK1, RDX, PRNP, ITGA5, NCAM1, CSNK2A1, ANK2, AP2A1, AP2M1,
Protein Size: 1257 - Poids moléculaire
- 138 kDa
- ID gène
- 3897
- NCBI Accession
- NM_000425, NP_000416
- UniProt
- P32004
- Pathways
- Synaptic Membrane
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