SPARC anticorps (C-Term)

N° du produit ABIN2789396

Cet anticorps Lapin Polyclonal détecte spécifiquement SPARC dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Lapin, Boeuf (Vache), Mouton, Poisson zèbre (Danio rerio), Chien, Chévre, Cobaye et Cheval.Il a été cité dans 1 publication.

Aperçu rapide pour SPARC anticorps (C-Term) (ABIN2789396)

Antigène: SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Mouton, Poisson zèbre (Danio rerio), Chien, Chévre, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPARC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SPARC anticorps

Épitope: C-Term

Fonction: SPARC Antibody - C-terminal region

Séquence: LAPLRAPLIP MEHCTTRFFE TCDLDNDKYI ALDEWAGCFG IKQKDIDKDL

Homologie: Cow: 93%, Dog: 86%, Goat: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 92%, Sheep: 93%, Zebrafish: 77%

Attributs du produit: This is a rabbit polyclonal antibody against SPARC. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63168-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SPARC (ABIN2789396)

Boyineni, Tanpure, Gnanamony, Antony, Fernández, Lin, Pinson, Gondi: "SPARC overexpression combined with radiation retards angiogenesis by suppressing VEGF-A via miR‑410 in human neuroblastoma cells." dans: International journal of oncology, Vol. 49, Issue 4, pp. 1394-406, (2016) (PubMed).

Détails sur SPARC

Antigène: SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))

Autre désignation: SPARC

Sujet:

Background Information: Secreted protein acidic and rich in cysteine/osteonectin/BM40, or SPARC, is a matrix-associated protein that elicits changes in cell shape, inhibits cell-cycle progression, and influences the synthesis of extracellular matrix (ECM).

Gene Name: Secreted protein, acidic, cysteine-rich (osteonectin)

Alternative Symbols: ON, ONT, OI17, BM-40

Protein Name: SPARC

Poids moléculaire: 35kDa

ID gène: 6678

NCBI Accession: NP_003109

UniProt: P09486

Pathways: Autophagy