TPMT anticorps (C-Term)

N° du produit ABIN2789428

Cet anticorps Lapin Polyclonal détecte spécifiquement TPMT dans WB. Il présente une réactivité envers Humain, Chien et Porc.

Aperçu rapide pour TPMT anticorps (C-Term) (ABIN2789428)

Antigène: TPMT (Thiopurine S-Methyltransferase (TPMT))

Reactivité: Humain, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPMT est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TPMT anticorps

Épitope: C-Term

Séquence: RGALVAINPG DRKCYADTMF SLLGKKFQYL LCVLSYDPTK HPGPPFYVPH

Homologie: Dog: 79%, Human: 100%, Pig: 79%

Attributs du produit: This is a rabbit polyclonal antibody against TPMT. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 245 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TPMT

Antigène: TPMT (Thiopurine S-Methyltransferase (TPMT))

Autre désignation: TPMT

Sujet: This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
Alias Symbols: -
Protein Interaction Partner: APP, UBC,
Protein Size: 245

Poids moléculaire: 27 kDa

ID gène: 7172

NCBI Accession: NM_000367, NP_000358

UniProt: P51580