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VKORC1 anticorps (N-Term)

VKORC1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2789450
  • Antigène Voir toutes VKORC1 Anticorps
    VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))
    Épitope
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval
    Hôte
    • 22
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    Cet anticorp VKORC1 est non-conjugé
    Application
    • 18
    • 18
    • 16
    • 5
    • 3
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    LHVKAARARD RDYRALCDVG TAISCSRVFS SRLPADTLGL CPDAAELPGV
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against VKORC1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N-terminal region of VKORC1
    Top Product
    Discover our top product VKORC1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 92 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))
    Autre désignation
    VKORC1 (VKORC1 Produits)
    Synonymes
    anticorps MGC89620, anticorps BP1071, anticorps CG33544, anticorps Dmel\\CG33544, anticorps HDC06808, anticorps VKORC1, anticorps EDTP308, anticorps IMAGE3455200, anticorps MST134, anticorps MST576, anticorps VKCFD2, anticorps VKOR, anticorps D7Wsu86e, anticorps vitamin K epoxide reductase complex, subunit 1, anticorps vitamin K epoxide reductase complex subunit 1, anticorps Vitamin-K epoxide reductase, anticorps VKORC1, anticorps vkorc1, anticorps Vkor, anticorps Vkorc1
    Sujet
    Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described.
    Alias Symbols: EDTP308, FLJ00289, IMAGE3455200, MGC2694, MST134, MST576, VKCFD2, VKOR
    Protein Interaction Partner: UBC, ILK, ZMYM6NB, TMEM242, SNORA12, TMEM256, ZCCHC24, METTL7B, SPTSSA, VKORC1L1, CCDC167, CCDC12, TMEM45B, KCNK17, JAGN1, SERP1, PPA2, TRAM1, TREX1, YIF1A, EBP, ARL6IP5, PROCR, IFITM3, ATP6AP2, BCAP31, PDIA6, HDAC6, HOMER2, VAPB, CLDN10, DPM2, REEP5, TF,
    Protein Size: 92
    Poids moléculaire
    10 kDa
    ID gène
    79001
    NCBI Accession
    NM_206824, NP_996560
    UniProt
    Q9BQB6
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