Desmoglein 1 anticorps (C-Term)

N° du produit ABIN2789462

L’anticorps anti-Desmoglein 1 Polyclonal Lapin est utilisé pour la détection de Desmoglein 1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval et Lapin. Il a été validé pour WB.

Aperçu rapide pour Desmoglein 1 anticorps (C-Term) (ABIN2789462)

Antigène: Desmoglein 1 (DSG1)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmoglein 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Desmoglein 1 anticorps

Épitope: C-Term

Fonction: DSG1 Antibody - C-terminal region

Séquence: GGIGLSSLGG TASIGHMRSS SDHHFNQTIG SASPSTARSR ITKYSTVQYS

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against DSG1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human DSG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63352-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Desmoglein 1

Antigène: Desmoglein 1 (DSG1)

Autre désignation: DSG1

Sujet:

Background Information: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.

Gene Name: desmoglein 1

Alternative Symbols: DG1, DSG, CDHF4, EPKHE, PPKS1, SPPK1, EPKHIA

Protein Name: desmoglein-1

Poids moléculaire: 44kDa

ID gène: 1828

NCBI Accession: NP_001933

UniProt: B7Z845

Pathways: Cell-Cell Junction Organization