DGAT1 anticorps (N-Term)
Aperçu rapide pour DGAT1 anticorps (N-Term) (ABIN2789488)
Antigène
Voir toutes DGAT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- HRLQDSLFSS DSGFSNYRGI LNWCVVMLIL SNARLFLENL IKYGILVDPI
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Homologie
- Cow: 100%, Dog: 93%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against Dgat1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Dgat1
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DGAT1 (Diacylglycerol O-Acyltransferase 1 (DGAT1))
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Autre désignation
- Dgat1
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Sujet
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Dgat1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. It may be involved in VLDL (very low density lipoprotein) assembly. In liver, Dgat1 plays a role in esterifying exogenous fatty acids to glycerol. It functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.
Alias Symbols: C75990, D15Ertd23e, Dgat
Protein Size: 498 -
Poids moléculaire
- 57 kDa
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ID gène
- 13350
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NCBI Accession
- NM_010046, NP_034176
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UniProt
- Q9Z2A7
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Pathways
- Hormone Transport
Antigène
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