BAG1 anticorps (N-Term)
Aperçu rapide pour BAG1 anticorps (N-Term) (ABIN2789515)
Antigène
Voir toutes BAG1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- BAG1 Antibody - N-terminal region
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Séquence
- LIFKGKSLKE METPLSALGI QDGCRVMLIG KKNSPQEEVE LKKLKHLEKS
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Homologie
- Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Pig: 86%, Rabbit: 91%, Zebrafish: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against BAG1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63477-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- BAG1 (BCL2-Associated Athanogene (BAG1))
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Autre désignation
- BAG1
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Sujet
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Background Information: The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Gene Name: BCL2-associated athanogene
Alternative Symbols: HAP, BAG-1, RAP46
Protein Name: BAG family molecular chaperone regulator 1
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Poids moléculaire
- 25kDa
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ID gène
- 573
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NCBI Accession
- NP_001165886
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UniProt
- Q99933
Antigène
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