CNR2 anticorps (C-Term)

N° du produit ABIN2789519

Cité dans 1 publication. Cet anticorps anti-CNR2 Polyclonal Lapin (ABIN2789519) détecte spécifiquement CNR2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris et Cheval.

Aperçu rapide pour CNR2 anticorps (C-Term) (ABIN2789519)

Antigène: CNR2 (Cannabinoid Receptor 2 (CNR2))

Reactivité: Humain, Rat, Souris, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNR2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CNR2 anticorps

Épitope: C-Term

Fonction: CNR2 Antibody - C-terminal region

Séquence: MVNPVIYALR SGEIRSSAHH CLAHWKKCVR GLGSEAKEEA PRSSVTETEA

Homologie: Horse: 83%, Human: 100%, Mouse: 79%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against CNR2. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63486-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CNR2 (ABIN2789519)

Wilhelmsen, Khakpour, Tran, Sheehan, Schumacher, Xu, Hellman: "The endocannabinoid/endovanilloid N-arachidonoyl dopamine (NADA) and synthetic cannabinoid WIN55,212-2 abate the inflammatory activation of human endothelial cells." dans: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13079-100, (2014) (PubMed).

Détails sur CNR2

Antigène: CNR2 (Cannabinoid Receptor 2 (CNR2))

Autre désignation: CNR2

Sujet:

Background Information: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.

Gene Name: Cannabinoid receptor 2 (macrophage)

Alternative Symbols: CB2, CX5, CB-2

Protein Name: Cannabinoid receptor 2

Poids moléculaire: 40kDa

ID gène: 1269

NCBI Accession: NP_001832

UniProt: P34972