CD207 anticorps (C-Term)

N° du produit ABIN2789525

Détail du produit anti-CD207 anticorps

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Porc, Cobaye, Cheval, Boeuf (Vache), Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD207 est non-conjugé

Application: Western Blotting (WB)

Séquence: GDWSWVDDTP FNKVQSARFW IPGEPNNAGN NEHCGNIKAP SLQAWNDAPC

Homologie: Cow: 92%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 83%, Rabbit: 83%, Rat: 83%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against CD207. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 328 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD207

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Autre désignation: CD207 (CD207 Produits)

Synonymes: anticorps CD207, anticorps CLEC4K, anticorps RGD1565913, anticorps CD207 molecule, anticorps CD207 antigen, anticorps CD207, anticorps Cd207

Sujet: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Alias Symbols: CLEC4K
Protein Interaction Partner: UBC,
Protein Size: 328

Poids moléculaire: 36 kDa

ID gène: 50489

NCBI Accession: NM_015717, NP_056532

UniProt: Q9UJ71