CCR10 anticorps (Middle Region)
Aperçu rapide pour CCR10 anticorps (Middle Region) (ABIN2789531)
Antigène
Voir toutes CCR10 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- ARALPAGPRP STPGRAHLVS VIVWLLSLLL ALPALLFSQD GQREGQRRCR
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 86%, Sheep: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against CCR10. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 362 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CCR10 (Chemokine (C-C Motif) Receptor 10 (CCR10))
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Autre désignation
- CCR10
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Sujet
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Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues, the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27, CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation.
Alias Symbols: GPR2
Protein Interaction Partner: CCL28, CXCL13, CCL27, CCL25, CCL19, CCR7, CCL7, CCL2, PRRC2A, CCL21,
Protein Size: 362 -
Poids moléculaire
- 40 kDa
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ID gène
- 2826
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NCBI Accession
- NM_016602, NP_057686
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UniProt
- P46092
Antigène
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