PANK2 anticorps (C-Term)
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- Antigène Voir toutes PANK2 Anticorps
- PANK2 (Pantothenate Kinase 2 (PANK2))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Cobaye, Lapin, Poisson zèbre (Danio rerio), Mouton, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PANK2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- ERFGLPGWAV ASSFGNMMSK EKREAVSKED LARATLITIT NNIGSIARMC
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against PANK2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product PANK2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 570 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PANK2 (Pantothenate Kinase 2 (PANK2))
- Autre désignation
- PANK2 (PANK2 Produits)
- Synonymes
- anticorps ATPANK2, anticorps F10M6.180, anticorps F10M6_180, anticorps pantothenate kinase 2, anticorps PANK2, anticorps C20orf48, anticorps HARP, anticorps HSS, anticorps NBIA1, anticorps PKAN, anticorps 4933409I19Rik, anticorps AI642621, anticorps pantothenate kinase 2, anticorps pantothenate kinase 2, mitochondrial, anticorps ribonuclease A family member 11 (inactive), anticorps PANK2, anticorps Tsp_01576, anticorps LOC100539295, anticorps Pank2, anticorps RNASE11
- Sujet
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This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms.
Alias Symbols: C20orf48, FLJ17232, HARP, HSS, MGC15053, NBIA1, PKAN
Protein Interaction Partner: UBC, DHX36, QRICH2, LXN, YWHAQ, VDAC1, RASGRF2,
Protein Size: 570 - Poids moléculaire
- 47 kDa
- ID gène
- 80025
- NCBI Accession
- NM_153638, NP_705902
- UniProt
- Q9BZ23
- Pathways
- Ribonucleoside Biosynthetic Process
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