CASQ2 anticorps (N-Term)
Aperçu rapide pour CASQ2 anticorps (N-Term) (ABIN2789644)
Antigène
Voir toutes CASQ2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- CASQ2 Antibody - N-terminal region
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Séquence
- DRVVSLSEKN FKQVLKKYDL LCLYYHEPVS SDKVTQKQFQ LKEIVLELVA
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Homologie
- Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against CASQ2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63849-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CASQ2 (Calsequestrin 2 (CASQ2))
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Autre désignation
- CASQ2
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Sujet
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Background Information: The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.
Gene Name: Calsequestrin 2 (cardiac muscle)
Alternative Symbols: PDIB2
Protein Name: Calsequestrin-2
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Poids moléculaire
- 46kDa
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ID gène
- 845
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NCBI Accession
- NP_001223
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UniProt
- O14958
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Pathways
- Negative Regulation of Transporter Activity
Antigène
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