CD276 anticorps (C-Term)

N° du produit ABIN2789671

Détail du produit anti-CD276 anticorps

Antigène: CD276

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Cheval, Lapin, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD276 est non-conjugé

Application: Western Blotting (WB)

Séquence: VCLIALLVAL AFVCWRKIKQ SCEEENAGAE DQDGEGEGSK TALQPLKHSD

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against CD276. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 316 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD276

Antigène: CD276

Autre désignation: CD276 (CD276 Produits)

Synonymes: anticorps sc:d0645, anticorps zgc:158279, anticorps 6030411F23Rik, anticorps AU016588, anticorps B7RP-2, anticorps B7h3, anticorps B7H3, anticorps 4Ig-B7-H3, anticorps B7-H3, anticorps CD276 molecule, anticorps CD276 molecule S homeolog, anticorps CD276 antigen, anticorps Cd276 molecule, anticorps CD276, anticorps cd276.S, anticorps cd276, anticorps Cd276

Sujet: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: B7-H3, B7H3, B7RP-2, 4Ig-B7-H3
Protein Interaction Partner: UBC, RYK,
Protein Size: 316

Poids moléculaire: 34 kDa

ID gène: 80381

NCBI Accession: NM_025240, NP_079516

Pathways: Cancer Immune Checkpoints