CD276 anticorps (C-Term)

N° du produit ABIN2789671

Cet anticorps Lapin Polyclonal détecte spécifiquement CD276 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Cheval, Boeuf (Vache), Lapin, Chien, Porc et Cobaye.

Aperçu rapide pour CD276 anticorps (C-Term) (ABIN2789671)

Antigène: CD276

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Lapin, Chien, Porc, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD276 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD276 anticorps

Épitope: C-Term

Fonction: CD276 Antibody - C-terminal region

Séquence: VCLIALLVAL AFVCWRKIKQ SCEEENAGAE DQDGEGEGSK TALQPLKHSD

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against CD276. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63929-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD276

Antigène: CD276

Autre désignation: CD276

Sujet:

Background Information: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: CD276 Molecule

Alternative Symbols: B7H3, B7-H3, B7RP-2, 4Ig-B7-H3

Protein Name: CD276 antigen

Poids moléculaire: 34kDa

ID gène: 80381

NCBI Accession: NP_079516

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints