LIMS1 anticorps (C-Term)
Aperçu rapide pour LIMS1 anticorps (C-Term) (ABIN2789690)
Antigène
Voir toutes LIMS1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Fonction
- LIMS1 Antibody - C-terminal region
-
Séquence
- VNCFACSTCN TKLTLKNKFV EFDMKPVCKK CYEKFPLELK KRLKKLAETL
-
Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
-
Attributs du produit
- This is a rabbit polyclonal antibody against LIMS1. It was validated on Western Blot.
-
Purification
- Affinity Purified
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Commentaires
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64006-100UG
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.5 mg/mL
-
Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- prevent freeze-thaw cycles
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
-
Autre désignation
- LIMS1
-
Sujet
-
Background Information: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
Gene Name: LIM and senescent cell antigen-like domains 1
Alternative Symbols: PINCH, PINCH1, PINCH-1
Protein Name: LIM and senescent cell antigen-like-containing domain protein 1
-
Poids moléculaire
- 44kDa
-
ID gène
- 3987
-
NCBI Accession
- NP_001180414
-
UniProt
- B7Z7R3
Antigène
-