RAP2A anticorps (C-Term)
Aperçu rapide pour RAP2A anticorps (C-Term) (ABIN2789703)
Antigène
Voir toutes RAP2A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- QIIRVKRYEK VPVILVGNKV DLESEREVSS SEGRALAEEW GCPFMETSAK
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Sheep: 93%, Zebrafish: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against RAP2A. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 183 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RAP2A (RAP2A, Member of RAS Oncogene Family (RAP2A))
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Autre désignation
- RAP2A
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Sujet
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RAP2A is a small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.
Alias Symbols: K-REV, KREV, RAP2, RbBP-30
Protein Interaction Partner: UBC, RPTOR, ELAVL1, RRP9, TM7SF2, PLG, SERPINA1, FTL, FKBP2, ENSA, EEF1A1, NEDD4, TNIK, RUNDC3A, GRIN1, RASIP1, RAPGEF5, RAPGEF6, ARHGAP29, RASSF5, MAP4K4, BMPR1B, GRIN2D, RGS14, RALGDS, SMAD1, TGFBR1, RAP2A, RAF1, MLLT4, FNTB, ACVR1, RAPGEF4, RAPGEF3, RA
Protein Size: 183 -
Poids moléculaire
- 20 kDa
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ID gène
- 5911
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NCBI Accession
- NM_021033, NP_066361
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UniProt
- P10114
Antigène
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