PDE11A anticorps (N-Term)

N° du produit ABIN2789716

Détail du produit anti-PDE11A anticorps

Antigène: PDE11A (phosphodiesterase 11A (PDE11A))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE11A est non-conjugé

Application: Western Blotting (WB)

Séquence: RRASQKELRK SFARSKAIHV NRTYDEQVTS RAQEPLSSVR RRALLRKASS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PDE11A. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 933 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PDE11A

Antigène: PDE11A (phosphodiesterase 11A (PDE11A))

Autre désignation: PDE11A (PDE11A Produits)

Synonymes: anticorps PPNAD2, anticorps 6330414F14Rik, anticorps A630086N24Rik, anticorps Gm350, anticorps PDE11A1, anticorps si:ch211-222f23.5, anticorps PDE11A, anticorps ppnad2, anticorps Pde11a, anticorps phosphodiesterase 11A, anticorps phosphodiesterase 11a, anticorps dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A, anticorps PDE11A, anticorps Pde11a, anticorps pde11a, anticorps LOC100470038

Sujet: The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ23693, MGC133355, MGC133356, PPNAD2
Protein Size: 933

Poids moléculaire: 105 kDa

ID gène: 50940

NCBI Accession: NM_016953, NP_058649

UniProt: Q9HCR9

Pathways: cAMP Metabolic Process